Ronald Christiaan ELGERSMA,Tijl HUIJBREGTS,Rudy Gerardus Elisabeth COUMANS
申请号：
US16338796
公开号：
US20200297859A1
申请日:
2017.10.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to linker-drug compounds (LDs) and antibody-drug conjugates (ADCs) comprising a non-linear self-immolative linker, which is cleavable or transformable under appropriate conditions and which reduces the hydrophobicity of the antibody-drug conjugate.
