The invention relates to a process for the preparation of P <;sub>; µ <;/sub>; particles comprising the steps consisting in: a) mixing: - P <;sub>; TiO2 <;/sub>; particles comprising a polysiloxane polymer comprising at least a polysiloxane chain covalently linked to TiO <;sub>; 2 <;/sub>; nanoparticles, said P <;sub>; TiO2 <;/sub>; particles being obtained from an alkoxysilane and a titanium alkoxide, with - P <;sub>; ZnOZnP <;/sub>; particles comprising a polysiloxane polymer comprising at least one polysiloxane chain covalently linked to nanoparticles comprising a composite of ZnO and zinc pyrithione, said P <;sub>; ZnOZnP <;particles / sub>; being obtained from an alkoxysilane, zinc acetate and particles of zinc pyrithione, to obtain a mixture, b) passing the mixture over a sieve to obtain particles P <;sub>; µ <;/ sub>; having a particle size distribution by volume, as measured by diffract laser ion, in which the volume median diameter D <;sub>; v50µ <;/sub>; is 1.0 to 5.0 µm and the volume diameter D <;sub>; v10µ <;/sub>; is at least 0, 1 μm, the particles P <;sub>; µ <;/sub>; obtainable, and their use for imparting self-cleaning and antimicrobial properties to a plastic part comprising a thermoplastic matrix.L'invention concerne un procédé pour la préparation de particules Pµ comprenant les étapes consistant à :a) mélanger :- des particules PTiO2 comprenant un polymère de polysiloxane comprenant au moins une chaîne de polysiloxane liée de manière covalente à des nanoparticules de TiO2, lesdites particules PTiO2 étant obtenues à partir d'un alcoxysilane et d'un alkoxyde de titane, avec- des particules PZnOZnP comprenant un polymère de polysiloxane comprenant au moins une chaîne de polysiloxane liée de manière covalente à des nanoparticules comprenant un composite de ZnO et de pyrithione de zinc, lesdites particules PZnOZnP étant obtenues à partir d'un alcoxysilane, d'ac