LEUNG DONMIENNE DOEN MUN,LUAN PENG,TANG YING,WITCHER DERRICK RYAN,YACHI PIA PAULIINA
申请号：
ZA201100261
公开号：
ZA201100261B
申请日:
2011.01.10
申请国别(地区):
ZA
年份:
2012
代理人:
摘要：
Monoclonal antibodies are provided that bind to the N-terminus of human hepcidin-25 and are characterized as having high affinity and selectivity for the polypeptide. The antibodies of the invention are useful for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment of various disorders, such as anemia, in a human subject. The antibodies of the invention are also useful as analytical tools, such as in sandwich ELISA.
