LEUNG, DONMIENNE DOEN MUN,LUAN, PENG,TANG, YING,WITCHER, DERRICK RYAN,YACHI, PIA PAULIINA
申请号：
PL09790908
公开号：
PL2328931T3
申请日:
2009.07.29
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
Monoclonal antibodies are provided that bind to the N-terminus of human hepcidin-25 and are characterized as having high affinity and selectivity for the polypeptide. The antibodies of the invention are useful for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment of various disorders, such as anemia, in a human subject. The antibodies of the invention are also useful as analytical tools, such as in sandwich ELISA.
