GALATSIS, PAUL,HENDERSON, JACLYN LOUISE,KORMOS, BETHANY LYN,KURUMBAIL, RAVI G.,REESE, MATTHEW RICHARD,STEPAN, ANTONIA FRIEDERIKE,VERHOEST, PATRICK ROBERT,WAGER, TRAVIS T.,PETTERSSON, MARTIN YOUNGJIN,G
申请号:
HK19101328
公开号:
HK1258857A1
申请日:
2019.01.25
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
wherein R1, R1a, R1b, R2, R4, R5, R6, X and Z are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising the compounds of Formula (I) and to use of the compounds in the treatment of diseases associated with LRRK2, such as neurodegenerative diseases including Parkinson's disease or Alzheimer's disease, cancer, Crohn's disease or leprosy.