Consejo Nacional De Investigaciones Cientificas Y Tecnicas;Fundación Articular;Inis Biotech LLC
发明人:
申请号:
EP14872823.1
公开号:
EP3082846B1
申请日:
2014.12.19
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.