Isoform of the TGF-beta receptor II

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专利权人:

Consejo Nacional de Investigaciones Cientificas y Técnicas;FUNDACIÓN ARTICULAR;INIS BIOTECH LLC

发明人:

Ricardo Alfredo Dewey,Benito Jorge Velasco Zamora,Tania Melina Rodríguez,Alejandra Carrea,Andrea Nancy Chisari,Marcelo Javier Perone

申请号：

US15105162

公开号：

US10233227B2

申请日:

2014.12.19

申请国别(地区):

US

年份:

2019

代理人:

摘要：

An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain； wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.

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