ISOFORM OF THE TGF-BETA RECEPTOR II

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专利权人:

Consejo Nacional De Investigaciones Cientificas Y Tecnicas

发明人:

DEWEY, Ricardo, Alfredo,VELASCO ZAMORA, Benito, Jorge,RODRIGUEZ, Tania, Melina,CARREA, Alejandra,CHISARI, Andrea, Nancy, Chisari,PERONE, Marcelo, Javier, Perone

申请号：

EP14872823

公开号：

EP3082846A4

申请日:

2014.12.19

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.

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