José Manuel Bartolomé-Nebreda;Gregor James MacDonald;Michiel Luc Maria Van Gool;Susana Conde-Ceide;Francisca Delgado-Jiménez
发明人:
José Manuel Bartolomé-Nebreda,Gregor James MacDonald,Michiel Luc Maria Van Gool,Susana Conde-Ceide,Francisca Delgado-Jiménez
申请号:
US13002413
公开号:
US08530474B2
申请日:
2009.07.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is concerned with novel substituted 6-(1-piperazinyl)-pyridazines of Formula (I)wherein R1, R2, R3 and X have the meaning defined in the claims, having 5-HT6-antagonistic properties. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said novel compound as an active ingredient as well as the use of said compounds as a medicine.