FRANCISCA DELGADO-JIMÉNEZ,GREGOR JAMES MACDONALD,JOSÉ MANUEL BARTOLOMÉ-NEBREDA,MICHIEL LUC MARIA VAN GOOL,SUSANA CONDE-CEIDE
申请号:
BRPI0915834
公开号:
BRPI0915834A2
申请日:
2009.07.01
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention is concerned with novel substituted 6-(1-piperazinyl)-pyridazines of Formula (I) wherein R1, R2, R3 and X have the meaning defined in the claims, having 5-HT6-antagonistic properties. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said novel compound as an active ingredient as well as the use of said compounds as a medicine.