BARTOLOME-NEBREDA, JOSE MANUEL,巴托伦 荷思,巴托倫 荷思,MACDONALD, GREGOR JAMES,麦当劳 葛瑞格,麥當勞 葛瑞格,VAN GOOL, MICHIEL LUC MARIA,凡古 米奇尔,凡古 米奇爾,CONDE-CEIDE, SUSANA,康德 苏珊娜,康德 蘇珊娜,DELGADO-JIMENEZ, FRANCISCA,德卡多 法兰思卡,德卡多
申请号：
TW098122349
公开号：
TWI436995B
申请日:
2009.07.02
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The present invention is concerned with novel substituted 6-(1-piperazinyl)-pyridazines of Formula (I)wherein R1, R2, R3and X have the meaning defined in the claims, having 5-HT6-antagonistic properties. The invention further relates to processes for preparing such novel compounds, pharmaceutical compounds comprising said novel compound as an active ingredient as well as the use of said compounds as a medicine.本發明關於具有5-HT6-拮抗性質的式(I)之新穎經取代之6-(1-六氫吡基)-嗒類:其中R1、R2、R3及X具有申請專利範圍中所定義之意義。本發明進一步關於製備此等新穎化合物之方法,包含該新穎化合物作為活性成分之醫藥組成物,以及該化合物作為藥劑之用途。
