The present invention relates to a method of producing a tableted chewing gumcomposition for oral administration of cannabinoids, the method comprises thestepsof: i) feeding a gum composition comprising water-insoluble gum base into anextruder from one or more feeding inlets, optionally including additionalingredients,ii) pressurizing the gum composition in the extruder while controllingtemperatureand pressure of the gum composition, optionally including further ingredientsfromone or more feeding inlets, iii) extruding the gum composition through a diemeans,iv) cutting the extruded gum composition in a liquid filled chamber, therebyobtaining a first population of particles comprising water-insoluble gum base,v)including the first population of particles with a second population ofparticlescomprising water-soluble chewing gum ingredients and one or more cannabinoids,the second population of particles being free of water-insoluble gum base,therebyobtaining a chewing gum composition and vi) tableting the chewing gumcomposition in a tablet pressing apparatus, thereby obtaining a tabletedchewing gumcomposition.
