PURPOSE: A composition containing horse bone extract for anti-inflammation is provided to suppress inflammatory cytokine generation and iNOS. CONSTITUTION: A composition for anti-inflammation contains ethanol extract or ethanol solution extract of horse bone as an active ingredient. The ethanol solution contains 70-80% of ethanol. The composition is a pharmaceutical composition or food composition. A composition for suppressing iNOS contains 70-80% of ethanol solution extract of horse bone as an active ingredient.본 발명은 항염증성 조성물을 개시한다. 구체적으로 본 발명은 말뼈 추출물을 유효성분으로 하는 항염증성 조성물을 개시한다.