Modulation du taux de libération de médicament en contrôlant la cinétique de la transition du pH dans des hydrogels

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专利权人:

Confluent Surgical Inc.

发明人:

申请号：

EP11250311.5

公开号：

EP2386290A3

申请日:

2011.03.15

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Methods and compositions relate to modulating the release profile of drug molecules from a hydrogel by controlling the kinetics of the pH transition of the hydrogel. The hydrogel is formed by in situ polymerization and includes a drug molecule having a pKa between the pH of the formed hydrogel and the physiologic environment in which the hydrogel is placed.

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中国工程科技知识中心

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