CANCER THERAPEUTIC TARGETING USING MUTANT P53-SPECIFIC SIRNAS

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专利权人:

SINGAPORE HEALTH SERVICES PTE LTD

发明人:

SABAPATHY, Kanaga

申请号：

SG11202007450X

公开号：

SG11202007450XA

申请日:

2019.02.21

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

Disclosed herein are nucleic acid sequences for targeting one or more point mutations within p53 gene. In particular, the site of point mutation in p53 is selected from the group consisting of R249, R248, R273 & R175. Also disclosed herein are methods for treating cancer in a subject, the method comprising administering to the subject one or more nucleic acid sequences disclosed herein.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/