An object of the present invention is to provide a medicinal drug muchimproved in anti tumor activity and excellent in safety. According to thepresent invention, there is provided a medicinal drug containing a compoundrepresented by the following general formula (1) or a salt thereof as anactive ingredient: [Formula 1] wherein X1 represents a nitrogen atom or agroup -CH=, R1 represents a group -Z-R6, in which Z represents a group -CO-, agroup -CH(OH)- or the like, R6 represents a 5- to 15-membered monocyclic,dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atomor a halogen atom, Y represents a group -O-, a group -CO-, a group -CH(OH)- ora lower alkylene group, and A represents [Formula 2] wherein R3 represents ahydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4represents an imidazolyl lower alkyl group or the like.