Alessandra Vitaliti,Anis Khusro Mir,Carmen Barske,Martin E. Schwab,Stefan Frentzel
申请号：
BRPI0818928
公开号：
BRPI0818928A2
申请日:
2008.10.27
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention provides a binding molecule which is capable of binding to the human NogoA polypeptide or human NiG with a dissociation constant<；1000 nM, a polynucleotide encoding such binding molecule； an expression vector comprising said polynucleotide； an expression system comprising a polynucleotide capable of producing a binding molecule； an isolated host cell which comprises an expression system as defined above； the use of such binding molecule as a pharmaceutical, especially in the treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system； a pharmaceutical composition comprising said binding molecule； and a method of treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system.
