IMPROVED NOGO-A BINDING MOLECULES AND PHARMACEUTICAL USE TEREOF

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专利权人:

NOVARTIS AG;UNIVERSITY OF ZURICH

发明人:

BARSKE, CARMEN,FRENTZEL, STEFAN,MIR, ANIS, KHURSO,SCHWAB, MARTIN, E.,VITALITI, ALESSANDRA

申请号：

MYPI 2010001822

公开号：

MY149546A

申请日:

2008.10.27

申请国别(地区):

MY

年份:

2013

代理人:

摘要：

THE PRESENT INVENTION PROVIDES A BINDING MOLECULE WHICH IS CAPABLE OF BINDING TO THE HUMAN NOGOA POLYPEPTIDE OR HUMAN NiG WITH A DISSOCIATION CONSTANT <； 1000 nM, A POLYNUCLEOTIDE ENCODING SUCH BINDING MOLECULE； AN EXPRESSION VECTOR COMPRISING SAID POLYNUCLEOTIDE； AN EXPRESSION SYSTEM COMPRISING A POLYNUCLEOTIDE CAPABLE OF PRODUCING A BINDING MOLECULE； AN ISOLATED HOST CELL WHICH COMPRISES AN EXPRESSION SYSTEM AS DEFINED ABOVE； THE USE OF SUCH BINDING MOLECULE AS A PHARMACEUTICAL, ESPECIALLY IN THE TREATMENT OF A DISEASE OF THE PERIPHERAL (PNS) AND/OR CENTRAL (CNS) NERVOUS SYSTEM； A PHARMACEUTICAL COMPOSITION COMPRISING SAID BINDING MOLECULE； AND A METHOD OF TREATMENT OF A DISEASE OF THE PERIPHERAL (PNS) AND/OR CENTRAL (CNS) NERVOUS SYSTEM.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/