KUHNERT, SVEN,MERLA, BEATRIX,KLESS, ACHIM,BAHRENBERG, GREGOR,SCHRODER, WOLFGANG
申请号:
NZ59562710
公开号:
NZ595627A
申请日:
2010.03.11
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
The invention relates to substituted 2-mercapto-3-aminopyridines of Formula (1), methods for the production thereof, medicaments containing said compounds, and the use of said compounds for producing medicaments suitable for treating pain, epilepsy, urinary incontinence, anxiety states, dependency, mania, bipolar disorders, migraine, cognitive diseases, dystonia-associated dyskinesias and/or urinary incontinence. Examples of such compounds are: 4-Fluoro-2-hydroxy-N-[2-[2-[[3-(trifluoromethyl)phenyl]sulfonyl]-ethylsulfanyl]-pyridin-3-yl] benzamide; N-[2-[2-[[3-(Trifluoromethyl)phenyl]sulfonyl]-ethylsulfanyl]-pyridin-3-yl]-tetrahydropyrane-2-carboxylic acid amide; 3-Hydroxy-N-[2-[2-[[3-(trifluoromethyl)phenyl]sulfonyl]-ethylsulfanyl]-pyridin-3-yl] benzamide; N-[2-[2-[[3-(Trifluoromethyl)phenyl]sulfonyl]-ethylsulfanyl]-pyridin-3-yl]-thiophene-2-carboxylic acid amide; N-[2-[2-(Benzenesulfonyl)-ethylsulfanyl]-pyridin-3-yl]-2-cyclohexyl acetamide.