Disclosed are heteroaryloxy-substituted benzoic acid amide compounds of Formula I, salts thereof, and methods for their preparation. Specific examples of compounds of Formula I include: N-(5-tert-butyl-3-methanesuIfonylamino-2-methoxy-phenyl)-4-methyl-3-(6-morpholin-4-yl-pyrimidin-4-yloxy)-benzamide, N-(5-tert-butyl-3-methanesulphonylamino-2-methoxy-phenyl)-3-chloro-4-methyl-5-(2-piperazin-1-yl-pyrimidin-4-yloxy)-benzamide, N-(5-tert-butyl-3-methanesulphonylamino-2-methoxy-pheny1)-4-methyl-3-[6-(4-methyl-piperazin-1-ylmethyl)-pyrimidin-4-yloxy]-benzamide, and N-(5-tert-butyl-3-methanesulphonylamino-2-methoxy-phenyl)-4-methyl-3-{ 6-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-pyrimidin-4-yloxy)benzamide. Compounds of Formula I are useful for treating respiratory complaints, such as COPD or asthma.
