THE GENERAL HOSPITAL CORPORATION;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
发明人:
RAINES, DOUGLAS E.,FORMAN, STUART A.,MILLER, KEITH W.,HUSAIN, SYED S.,CUNY, GREGORY D.,COTTEN, JOSEPH F.
申请号：
CA2767112
公开号：
CA2767112C
申请日:
2010.07.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT； R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1； n is an integer from 0 to 5； each R3 is independently halogen or R2； R4 and R5 are independently H, halogen, CN or CF3； L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene； and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.
