Hird, Alexander,Belmonte, Matthew Alan,Yang, Wenzhan,Secrist, John Paul,Robbins, Daniel William,Kazmirski, Steven Lee,Wu, Dedong,Peng, Bo,Johannes, Jeffrey,Lamb, Michelle Laurae,Ye, Qing,Zheng, Xiaola
申请号:
HRP20200673
公开号:
HRP20200673T1
申请日:
2020.04.28
申请国别(地区):
HR
年份:
2020
代理人:
摘要:
and enantiomers and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions of 17-chloro-5,13,14,22-tetramethyl-28-oxa-2,9-dithia-5,6,12,13,22-pentaazaheptacyclo[27.7.1.14,7.011,15.016,21.020,24.030,35]octatriaconta-1(37),4(38),6,11,14,16,18,20,23,29,31,33,35-tridecaene-23-carboxylic acid, and enantiomers and pharmaceutically acceptable salts thereof, and methods of treating cancer with such compounds and compositions.