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תולדות n–הידרוקסילסולפונאמיד כתורמי ניטרוקסיל חדשים שימושיים פיזיולוגית
专利权人:
CARDIOXYL PHARMACEUTICALS INC.;THE JOHNS HOPKINS UNIVERSITY;JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
发明人:
申请号:
IL19383908
公开号:
IL193839A
申请日:
2008.09.02
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N- hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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