METHOD FOR INDUCING T CELLS FOR CELL-BASED IMMUNOTHERAPY FROM PLURIPOTENT STEM CELLS

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专利权人:

KYOTO UNIVERSITY

发明人:

KANEKO, SHIN,KAWAMOTO, HIROSHI,MASUDA, KYOKO,MINAGAWA, ATSUTAKA,HOTTA, AKITSU,SHIMAZU, YUTAKA,ICHISE, HIROSHI

申请号：

SG11201701191W

公开号：

SG11201701191WA

申请日:

2015.07.17

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

Provided is a method for inducing T cells for a cell-based immunotherapy, comprising the steps of: (1) providing Rag 1 and/or Rag2 gene knockout human pluripotent stem cells bearing genes encoding a T cell receptor specific for a desired antigen, and (2) inducing T cells from the pluripotent stem cells of step (1). Further provided are a cell-based immunotherapy method that uses the T cells for the cell-based immunotherapy and an iPS cell bank for the cell-based immunotherapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/