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Production method for pluripotent stem cells having antigen-specific t cell receptor gene
专利权人:
Hiroshi Kawamoto
发明人:
Kawamoto, Hiroshi,Kaneko, Shin,Masuda, Kyoko,Maeda, Takuya,Nagano, Seiji,Katsura, Yoshimoto
申请号:
AU2015290561
公开号:
AU2015290561A1
申请日:
2015.07.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided is a method for inducing T cells for immunotherapy, including: a step (1) in which human pluripotent stem cells having a WT1 antigen-specific T cell receptor or an Epstein-Barr virus antigen-specific T cell receptor are provided; and a step (2) in which progenitor T cells or mature T cells are induced from the pluripotent stem cells from step (1). iPS cells, in particular, can be suitably used as the pluripotent stem cells. The human pluripotent stem cells having an antigen-specific T cell receptor can be obtained by inducing iPS cells from T cells having the desired antigen specificity or by introducing the desired antigen-specific T cell receptor to the iPS cells. T cells obtained by using this method can be used in immunotherapy for a variety of immune-related diseases including cancer and infectious diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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