Compositions and methods for enhancing an immune response with an adjuvant composition comprising: an anti-dendritic cell (DC)-specific antibody or fragment thereof conjugated to at least a portion of a flagellin and a pharmaceutically acceptable carrier are disclosed herein. The conjugate and agonist are each comprised in an amount such that, in combination with the other, are effective to produce the immune response in a human or animal subject in need of immunostimulation.本文揭示組合物及使用佐劑組合物增強免疫反應的方法,該佐劑組合物包含:與鞭毛蛋白之至少一部分結合之抗樹突狀細胞(DC)特異性抗體或其片段;及醫藥學上可接受之載劑。該結合物及促效劑各包含與另一者組合可在需要免疫刺激之人類或動物個體中有效引起免疫反應的量。(無元件符號說明)
