ZURAWSKI, GERARD,BANCHEREAU, JACQUES F.,FLAMAR, ANNE-LAURE,KANE, ROBERT R.
申请号：
TW101107940
公开号：
TW201247706A
申请日:
2012.03.08
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The present invention includes compositions and methods for enhancing an immune response with an adjuvant composition comprising: an anti-dendritic cell (DC)-specific antibody or fragment thereof conjugated to at least a portion of Toll-Like Receptor (TLR) agonist, more specifically a TLR7 ligand (TLR7L), and a pharmaceutically acceptable carrier, wherein the conjugate and agonist are each comprised in an amount such that, in combination with the other, are effective to produce the immune response in a human or animal subject in need of immunostimulation.
