Jacques F. Banchereau;Anne-Laure Flamar;Robert R. Kane;Gerard Zurawski
发明人:
Gerard Zurawski,Jacques F. Banchereau,Anne-Laure Flamar,Robert R. Kane
申请号：
US13415564
公开号：
US20120231023A1
申请日:
2012.03.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention includes compositions and methods for enhancing an immune response with an adjuvant composition comprising: an anti-dendritic cell (DC)-specific antibody or fragment thereof conjugated to at least a portion of Toll-Like Receptor (TLR) agonist, more specifically a TLR7 ligand (TLR7L), and a pharmaceutically acceptable carrier, wherein the conjugate and agonist are each comprised in an amount such that, in combination with the other, are effective to produce the immune response in a human or animal subject in need of immunostimulation.
