PROCESS FOR THE PREPARATION OF MEMANTINE AND ITS HYDROCHLORIC ACID SALT FORM

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专利权人:

KRKA; d.d.; Novo mesto

发明人:

TIHI Jaroslav,TIHI Jaroslav,MELEH Marija,MELEH Marija,VRECER Franc,VRECER Franc,ZUPET Rok,ZUPET Rok,PUCELJ Joze,PUCELJ Joze,PELKO Mitja,PELKO Mitja

申请号：

SI200731960

公开号：

SI2097372T1

申请日:

2007.10.05

申请国别(地区):

SI

年份:

2017

代理人:

摘要：

The present invention relates to the synthesis of 1-amino-3,5-dimethyladamantane ("memantine") and its hydrochloric acid salt form. In particular a new intermediate (N-chloro-acetylamino-3,5-dimethyladamantane) for the synthesis of memantine as well as a new process for the preparation of memantine and its hydrochloric acid salt form using said intermediate is disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/