ТРОГДЕН Джон Т. (US),САЛАМЕХ Аднан (US),ПУДЖАРА Четан П. (US)
申请号：
RU2012122616/15
公开号：
RU2012122616A
申请日:
2010.11.05
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. Composition for hair growth by topical application, comprising at least one penetration enhancer； from 0.01% w / w to 0.3% w / w of a cyclopentanoic heptanoic acid, 2-cycloalkyl or arylalkyl compound of formula I: wherein the dashed bonds indicate the presence or absence of a double bond, which may be in a cis or trans configuration, A is an alkylene or alkenyl radical having from two to six carbon atoms, which may be interrupted by one or more hydroxy radicals and substituted by one or more hydroxy, oxo, alkyl or alkyl carboxyl groups, where the alkyl radical contains from one to six carbon atoms； B is a cycloalkyl radical having three to seven carbon atoms, or an aryl radical selected from the group consisting of hydrogen, a lower alkyl radical having four to ten carbon atoms, where the heteroatom is selected from the group consisting of nitrogen, oxygen and sulfur； X is —N (R), where R is selected from the group consisting of hydrogen, a lower alkyl radical having one to six carbon atoms, and R is a lower alkyl radical having one to six carbon atoms； Z is O； one of R and R = O, —OH or a group —O (CO) R, and the other is —OH or —O (CO) R, or R = O and R is H, where R is a saturated or unsaturated acyclic hydrocarbon group having from 1 to about 20 carbon atoms, or - (CH) mR, where m is 0 or an integer from 1 to 10, and R is a cycloalkyl radical having from three to seven carbon atoms, or a hydrocarbylaryl or heteroaryl radical, as defined above in free form or its pharmaceutically acceptable salt, in��1. Композиция для роста волос путем местного применения, включающаяпо меньшей мере, один интенсификатор проникновения； иот 0,01% в/в до 0,3% в/в соединения циклопентановой гептановой кислоты, 2-циклоалкила или арилалкила, формулы I:где пунктирные связи отображают наличие или отсутствие двойной связи, которая может быть в цис или транс конфигурации, A является алкиленовым или алкениловым радикалом, имеющим от двух до шести атомов углерода, который может быть прерва
