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Melanocortin receptor antagonist compounds, processes to prepare them and their use in human and cosmetic medicine
专利权人:
GALDERMA RESEARCH & DEVELOPMENT
发明人:
BOUIX-PETER, CLAIRE,CARLAVAN, ISABELLE,SOULET, CATHERINE,PARNET, VÉRONIQUE,VOEGEL, JOHANNES
申请号:
ES09744693
公开号:
ES2483738T3
申请日:
2009.11.04
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Compounds of general formula (I) indicated below: ** Formula ** in which: R 1 represents a hydrogen atom, an aryl that is an unsubstituted phenyl or naphthyl, a substituted aryl that is a phenyl or a naphthyl substituted with one or more groups of atoms chosen from an alkyl, an alkoxy, a halogen, a hydroxyl, a cyano, a trifluoromethyl and a nitro, an alkyl, a cycloalkyl or a cycloalkylalkyl, R2 represents a hydrogen atom, a hydroxyl or a lower alkyl which is a linear or branched saturated or unsaturated hydrocarbon-based chain containing from 1 to 4 carbon atoms or an unsaturated chain containing from 2 to 4 carbon atoms, a substituted lower alkyl which is a hydrocarbon-based chain saturated or linear or branched unsaturated containing 1 to 4 carbon atoms and substituted with one or more halogen atoms or with a hydroxyl, or an unsaturated hydrocarbon-based chain containing 2 to 4 carbon atoms carbon and substituted with one or more halogen atoms or with a hydroxyl, a higher alkyl which is a saturated or unsaturated linear or branched hydrocarbon chain containing from 5 to 10 carbon atoms, a substituted higher alkyl which is a chain based in saturated or unsaturated linear or branched hydrocarbon containing from 5 to 10 carbon atoms and substituted with one or more halogen atoms or with a hydroxyl, a cycloalkyl, a cycloalkylalkyl, a lower alkoxy which is an oxygen atom substituted with an alkyl lower, a substituted lower alkoxy which is an oxygen atom substituted with a lower alkyl substituted a higher alkoxy which is an oxygen atom substituted with a higher alkyl, a substituted higher alkoxy which is an oxygen atom substituted with a substituted higher alkyl, a cycloalkylalkoxy, an acyloxy, an acyl, an alkoxycarbonyl, a carboxamide, a carboxylic acid, a cyano or an amino disusti tuido with an acyl and an aryl which is a phenyl or naphthyl or unsubstituted alkyl, R3 represents an aralkyl which is an alkyl substituted with an aryl or a substituted aralkyl which is an
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