Kennie U. Dee;Wendell G. Mendoza;Rita Josefina M. Santos
发明人:
Wendell G. Mendoza,Rita Josefina M. Santos,Kennie U. Dee
申请号:
US14431374
公开号:
US09295659B2
申请日:
2013.02.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a high dose extended-release potassium citrate tablet containing carnauba wax, which contains a first portion of melt- or heat-granulated carnauba wax and potassium citrate; and a second portion of non-granulated potassium citrate. The high dose extended-release potassium citrate tablet of this invention has robust batch-to-batch dissolution and friability; and leads to improved production capacity and reduced production cost.