COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND THERAPY OF CLOSTRIDIUM DIFFICILE INFECTION

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专利权人:

The Rockefeller University

发明人:

GHOSE-PAUL, Chandrabali,HO, David H.

申请号：

EP14855019

公开号：

EP3060246A4

申请日:

2014.10.23

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Provided are compositions and methods for prophylaxis and/or therapy of C. difficile infection, and for inhibiting dissemination of C. difficile spores. The compositions contain C. difficile proteins, including distinct proteins and fusions of C. difficile CD 1067, BclA1, SleC, CotA, Spl7, FliC, FliD, CD toxin A, CD toxin B, and combinations thereof. The methods include prophylaxis and/or therapy of C. difficile infection by administering to a subject in need a composition that includes the C. difficile protein(s).

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