作為MEK抑制物質的5-取代-2-苯基氨基-苯甲酰胺類

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

ISSHIKI, YOSHIAKI,KOHCHI, YASUNORI,MIZUGUCHI, EISAKU,IIKURA, HITOSHI,MATSUBARA, YASUAKI,TSUJII, SHINJI,SHIMMA, NOBUO,MIWA, MASANORI,AIDA, SATOSHI,KOHCHI, MASAMI,MURATA, TAKESHI,ASO, KOSUKE

申请号：

HK08107296.8

公开号：

HK1116766B

申请日:

2008.07.02

申请国别(地区):

HK

年份:

2012

代理人:

摘要：

An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R 1 , R 2 , R 3 , R 4 , and X are the same as defined in the present patent application].

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中国工程科技知识中心

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http://www.ckcest.cn/home/