Relating to compounds of formula (i) where RX is Hydrogen or C1 - C3 alkyl R is Hydrogen or C1 - C3 alkyl A1, A2, A3 and A4 is n, Methyl, among others L1 is o, NH,Among others, RX1 is selected from \u2013cn, among others G1 is phenyl Compounds, among others they are preferred: {2 - [4 - (2,2 - difluorociclopropil) methoxy] - 5 - (ethylsulfonyl) phenyl) - 6 - methyl - 2 - {[4 - (pyridin-4-yl) piperazin-1-yl] methyl} - 1.6 - dihydro 7h pyrrolo [2,3-c] pyridin - 4 - 4 - 2 - {one [(2)2 - difluorociclopropil) methoxy] - 5 - (ethylsulfonyl) phenyl) - 6 - methyl - 2 - {[4 - (1,3 - thiazol-2-yl) piperazin-1-yl] methyl} - 1.6 - dihydro 7h pyrrolo [2,3-c] pyridin - 4 - ona.Also provided are Pharmaceutical compositions comprising one or more compounds of formula (i) and the pharmaceutically acceptable salts thereof,They are useful as agents in the treatment of diseases and clinical States, including inflammatory diseases, cancer, and AIDSReferida a compuestos de formula (I) donde RX es hidrogeno o C1-C3 alquilo RY es hidrogeno o C1-C3 alquilo A1, A2, A3 Y A4 es N, metilo, entre otros L1 es O, NH, entre otros RX1 se selecciona entre –CN, entre otros G1 es fenilo, entre otros Son compuestos preferidos: 4-{2-[(2,2-difluorociclopropil)metoxi]-5-(etilsulfonil)fenil}-6-metil-2-{[4-(piridin-4-il)piperazin-1-il]metil}-1,6-dihidro-7h-pirrolo[2,3-c]piridin-4-ona 4-{2-[(2,2-difluorociclopropil)metoxi]-5-(etilsulfonil)fenil}-6-metil-2-{[4-(1,3-tiazol-2-il)piperazin-1-il]metil}-1,6-dihidro-7h-pirrolo[2,3-c]piridin-4-ona. Tambien se proveen composiciones farmaceuticas que comprenden uno o mas compuestos de formula (I) y sales farmaceuticamente aceptables de los mismos, que son utiles como agentes en el tratamiento de enfermedades y estados clinicos, incluyendo enfermedades inflamatorias, cancer, y sida
