ISHIHARA SANGYO KAISHA, LTD.;CHUBU UNIVERSITY EDUCATIONAL FOUNDATION
发明人:
YAMAGUCHI, SEIJI,山口诚二,山口誠二,KAJI, SEIJI,梶诚司,梶誠司
申请号：
TW107124906
公开号：
TW201919719A
申请日:
2018.07.19
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention addresses the problem of providing: a three-dimensional structure with biological activity wherein the surface of a three-dimensional structure main body has recesses and/or protrusions and is covered with a coating film comprising a hydrolysis product of a titanium alkoxide with high adhesion strength； and a production method therefor. This three-dimensional structure with biological activity comprises: a three-dimensional structure main body having recesses and/or protrusions on the surface and comprising a polymer； and a 10-200 nm thick coating film formed on the surface of the three-dimensional structure main body and comprising a hydrolysis product of a titanium alkoxide. When the recesses and/or protrusions on the surface of the three-dimensional structure are observed with a scanning electron microscope at a magnification of 300, no cracks or separation of the coating film is observed. The coating film has biological activity when evaluated under the conditions defined by ISO 23317.本發明之課題為提供於表面具有凹部及/或凸部之立體構造物本體的表面，以高的密合強度被覆有由烷氧化鈦水解生成物所成之被覆膜而成的具有生體活性的立體構造物及其製造方法。 本發明之具有生體活性的立體構造物，具有由表面具有凹部及/或凸部之聚合物所成之立體構造物本體，與形成於該立體構造物本體之表面的厚度10~200nm的由烷氧化鈦水解生成物所成之被覆膜而成，前述被覆膜，以掃描型電子顯微鏡以300倍之倍率觀察於立體構造物之表面的凹部及/或凸部時，觀察不到被覆膜之破裂剝離，於以ISO23317所規定之條件進行評估時，係具有生體活性者。
