LASTOVICH, Alexander,ALARCON, Jason,DEKKER, John,HAIDER, M.,MIKSZTA, John,MARTIN, Frank,O'CONNOR, Scott
申请号：
ES03749157
公开号：
ES2599304T3
申请日:
2003.08.27
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A matrix (101) of microprotrusions for rotationally administering a fluid substance to tissue, said matrix (101) comprising: at least one circular stage (102), said circular stage (102) comprising a surface for microprotuberances and a stage edge ( 102) having a thickness, wherein said microprotube surface is suitable for fixing a plurality of microprotubes (10) thereon or on it； a plurality of microprotuberances (10) fixed on or on said microprotube surface 10 of said circular stage (102) in a radial matrix (101), wherein each of said microprotuberances (10) comprises at least one scraping edge； and at least one fluid substance retention means, said substance retention means being selected from the group consisting of separation between microprotrusions, one or more recesses between said microprotubes (10), one or more areas devoid of microprotubes (10), a or more areas with reduced microprotube density, one or more areas with microprotube (10) fixed to the stage (102) following a pattern adapted to direct said substance into said matrix (101), one or more channels on the surface for fixing microprotuberances of the stage (102), and combinations thereof, wherein said fluid substance retaining means retains said fluid substance releasably when the matrix (101) is used, thus allowing any fluid substance that does not administered immediately to the tissue remain in the matrix (101).Una matriz (101) de microprotuberancias para administrar por rotación una sustancia fluida a tejido, comprendiendo dicha matriz (101): al menos una platina circular (102), comprendiendo dicha platina circular (102) una superficie para microprotuberancias y un borde de platina (102) que tiene un grosor, en donde dicha superficie para microprotuberancias es adecuada para fijar una pluralidad de microprotuberancias (10) sobre la misma o en la misma； una pluralidad de microprotuberancias (10) fijadas en o sobre dicha superficie para microprotuberancias 10 de dicha platina circular (102) en una
