TICE, David,XIAO, Zhan,KINNEER, Krista,REBELATTO, Marlon,CHOWDHURY, Partha S.,STEINER, Philipp
申请号：
DK12852317
公开号：
DK2797957T3
申请日:
2012.11.20
申请国别(地区):
DK
年份:
2019
代理人:
摘要：
The present invention relates to antibodies and antigen binding fragments thereof that bind the extracellular domain of the HER3 receptor and inhibit various HER3 receptor related functions via ligand-dependent and/or ligand-independent mechanisms. Also provided are compositions with increased half-life. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER3 mediated signal transduction.
