BINDING MOLECULES SPECIFIC FOR HER3 AND USES THEREOF

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专利权人:

MEDIMMUNE; LLC

发明人:

CHOWDHURY, PARTHA S.,TICE, DAVID,XIAO, ZHAN,STEINER, PHILIPP,KINNEER, KRISTA,REBELATTO, MARLON

申请号：

EP12852317

公开号：

EP2797957A4

申请日:

2012.11.20

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to antibodies and antigen binding fragments thereof that bind the extracellular domain of the HER3 receptor and inhibit various HER3 receptor related functions via ligand-dependent and/or ligand-independent mechanisms. Also provided are compositions with increased half-life. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER3 mediated signal transduction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/