Peptide vaccine using mimic molecules of amyloid β peptide

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专利权人:

Kazuhisa Sugimura

发明人:

Kazuhisa Sugimura

申请号：

US12739651

公开号：

US08586706B2

申请日:

2008.10.22

申请国别(地区):

US

年份:

2013

代理人:

摘要：

This invention is intended to discover a peptide that induces production of an antibody specific for an abnormal amyloid β peptide from mimic peptides of the amyloid β peptide and to utilize the same as a vaccine or immunogen. This invention relates to a pharmaceutical composition containing a peptide consisting of 8 to 30 amino acid residues, wherein the peptide comprises at least one of an amino acid sequence represented by formula (I): Tyr-Gly-Thr-Lys-Pro-Trp-Met (SEQ ID NO: 28) (I), and an amino acid sequence represented by formula (II): Leu-Asp-Ile-Phe-Ala-Pro-Ile (SEQ ID NO: 29) (II) or a conjugate of such peptide and a carrier.

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