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ORGANOTRIFLUOROBORATE MIMICS OF AMINO ACIDS AND USES THEREOF
专利权人:
发明人:
申请号:
EP16787230.8
公开号:
EP3288952A1
申请日:
2016.04.29
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed are boron mimics of amino acids which are compounds, salts, solvates, or stereoisomers of the Formula (I): wherein A, R.1, R2, and R3 are defined herein, and processes for the preparation of the compounds, salts, solvates, or stereoisomers. The compounds, salts, solvates, or stereoisomers of Formula (I) may be used in boron neutron capture therapy. The compounds, salts, solvates, or stereoisomers of Formula (I) with at least one fluorine being, 18F are useful for imaging tumors using positron emission tomography and for evaluating the treatment potential of anti-cancer drugs.
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