Kong, Leopold,Wilson, Ian A.,De Val, Natalia,Ward, Andrew B.,Burton, Dennis,He, Linling,Zhu, Jiang
申请号：
AU2017259275
公开号：
AU2017259275A1
申请日:
2017.05.01
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention provides HiV-1 vaccine immunogens. Some of the immunogens contain a soluble gpl40-derived protein that harbors a modified N- terminus of the HRl region in gp41. Some of the immunogens contain an HIV-1 Env- derived trimer protein that is presented on 8 nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
