KONG, LEOPOLD,WILSON, IAN A.,DE VAL, NATALIA,WARD, ANDREW B.,BURTON, DENNIS,HE, LINLING,ZHU, JIANG
申请号：
CA3022826
公开号：
CA3022826A1
申请日:
2017.05.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides HiV-1 vaccine immunogens. Some of the immunogens contain a soluble gpl40-derived protein that harbors a modified N- terminus of the HRl region in gp41. Some of the immunogens contain an HIV-1 Env- derived trimer protein that is presented on 8 nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.
