JAIN MOHAN BABULAL ( MAC CHEM PRODUCTS INDIA PVT. LTD. 304 TOWN CENTRE ANDHERI-KURLA ROAD ANDHERI (EAST) MUMBAI-400059 MAHARASHTRA INDIA. ),HE XIAO,SHEN XIN,LIAO LIXIN,ZHAN HUAXING,LIN FUXING,YANG JID
申请号：
IN1092/MUM/2008
公开号：
IN255652B
申请日:
2008.05.23
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
Disclosed herein is a process for preparation of imatinib free base which comprises condensing N-(4-methyl-3-amino phenyl)-4-(4-methyl-piperazinyl-l-methyl)-benzamide with 4-methyl-(3-pyridyl)-2-pyrimidone, using polypeptide coupling agent in the presence of organic base as acid absorbing reagent in an organic solvent to form imatinib.
