System and method sympathetectomy neuromodulation for process control is disclosed. The micro- ablation procedure of system controlled is disclosed. Seal wire includes the conduct part physiology monitor session that one or more sensors or electrode are used to access and record physiologic information parenchymatous organ out of one or more dissection snuffbottles, and diagnostic test or a neuromodulation process are disclosed. Seal wire includes one or more sensors and/or is used for energy transportation means, is disclosed for executing neuromodulation process in the intracorporal small container of body.