NONIMMUNOSUPPRESSIVE CYCLOSPORINE ANALOGUE MOLECULES

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专利权人:

ISOTECHNIKA PHARMA INC.

发明人:

ABEL, MARK, D,CZAJKOWSKI, DAVID, P,FENSKE, BRUCE, W,HEGMANS, ALEXANDER,MCGLADE, DAVE,TREPANIER, DAN, J,URE, DARREN, R,SUGIYAMA, SHIN

申请号：

NZ59051709

公开号：

NZ590517A

申请日:

2009.07.03

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

NONIMMUNOSUPPRESSIVE CYCLOSPORINE ANALOGUE MOLECULES Provided are cyclosporine analogues comprising backbone of depicted Formula I, wherein R' is H or acetyl； R1 is a straight chain or branched alkane or alkene group from 2 to 15 carbon atoms in length； and R2 is as defined. The compounds are useful in treating cyclophilin mediated diseases, including various infections, inflammations, cancers and cellular, tissue or organ degeneration.

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http://www.ckcest.cn/home/