Istituto Di Ricerche Di Biologia Molecolare P. Angeletti SpA
发明人:
Jones, Philip,Branca, Danila,Boueres, Julia Kay,Muraglia, Ester,Schultz-Fademrecht, Carsten,Ontoria Ontoria, Jesus Maria,Ferrigno, Federica,Scarpelli, Rita,Orvieto, Federica
申请号：
AU2007232297
公开号：
AU2007232297B2
申请日:
2007.04.02
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to compounds of formula (I) and pharmaceuticallyacceptable salts or tautomers thereof which are inhibitors of poly (ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatorydiseases, reperfusion injuries, ischemic conditions, stroke, renal failure,cardiovascular diseases, vascular diseases other than cardiovascular diseases,diabetes, neurodegenerative diseases, retroviral infection, retinal damageor skin senescence and UV-induced skin damage, and as chemo- or radiosensitizersfor cancer treatment.
