ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.
发明人:
JONES, PHILIP,ONTORIA ONTORIA, JESUS MARIA,SCARPELLI, RITA,SCHULTZ-FADEMRECHT, CARSTEN
申请号：
CA2674436
公开号：
CA2674436C
申请日:
2008.01.08
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerat ive diseases, retroviral infection, retinal damage or skin senescence and UV- induced skin damage, and as chemo- and/or radiosensitizers for cancer treatment.
