Novel methods and devices are disclosed for automatically producing a simulated moving bed chromatography system and parameters from input of a fixed-bed liquid chromatography process directed at separating the same product. Tools and algorithms are provided which automatically convert fixed-bed process parameters into an executable simulated moving bed chromatography program. Familiar tabular input interfaces and a unique circular phase map of the simulated moving bed system that is generated according to input data makes the methods and apparatus of the invention extremely user-friendly and easy to use.
