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ENGINEERED COMMENSAL BACTERIA AND METHODS OF USE
专利权人:
The Regents of the University of California
发明人:
Steven Brown,Amir Zarrinpar,Juliet Snyder
申请号:
US16604138
公开号:
US20200056145A1
申请日:
2018.04.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided are compositions comprising populations of commensal bacteria isolated from a microbiome sample of a mammalian subject and engineered to express a heterologous polynucleotide, compositions comprising such engineered commensal bacteria and methods of use for delivering a therapeutic polypeptide to a mammal, e.g, by administering the engineered commensal/native bacteria.
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